Andre Langer
Phone: ++49-4488-1221, Fax: ++49-4488-861837
e-mail: andre.langer@web.de
W4 1-191
My aim is to describe those cells in mouseretina, which contain Parvalbumin.
Parvalbumin is a member of the family of Ca2+ binding proteins, the socalled
CaBPīs which have received more attention from neurobiologists over the
last few years. The cellular distributions of this CaBPīs seam to be quite
specific. Thatīs why they are thought to be able to be used as selective
markers of nerv cells.
As you can see on the picture down, indeed just some cells of mouseretina
show parvalbumin like immunoreactivity. Which cells are these? How frequent
are they and where in the retina are they located?
Is possible to describe the morphological subtypes of these parvalbumin-positiv
cells?
On these questions I do my diploma here in Oldenburg. Therefore I use
immunohistochemical methods, mircroscope-drawings (camera lucida, as you
can see below) and statistics. I analyse the somasize, the size of the
dendriticfield and in which sublamina of the Inner Plexiform Layer (IPL)
the dendrites of the stained cells ramify.
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